Title: AB blood type and the risk of cognitive decline Introduction: Mr. Li, a 49-year-old businessman, was diagnosed with early-stage Alzheimer's disease, causing a significant impact on his and his wife's lives. 1. AB blood type and accelerated cognitive decline: Research published in JAMANeurology suggests that individuals with AB blood type have an 82% higher probability of experiencing cognitive decline compared to other blood types.

This is attributed to higher levels of the factor VIII protein, which can lead to impaired brain function and increased risk of dementia. 2. Lower risk for individuals with blood type O: People with blood type O have a lower risk of developing cognitive impairments. This is because they have more grey matter in areas of the brain responsible for memory, resulting in stronger neural connections and better memory function.

Prevention strategies to reduce the risk of dementia: Director Niu Guowei of the Beijing Xiaotangshan Hospital's Aerobic Exercise Center suggests several preventive measures: 1. Manage hypertension, hyperlipidemia, and hyperglycemia: Keeping blood pressure between 90-140mmHg, maintaining a healthy weight, and controlling blood glucose levels are crucial. Regular monitoring of these parameters, especially after the age of 35, is recommended.

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