1: Introduction - Mr. Liu, a 60-year-old man, has been experiencing occasional headaches for about 2 years. - He has been taking analgesics to relieve the pain, increasing the dosage over time. - Recently, he started feeling weak and experiencing pain in the lower back and abdomen. - After visiting the hospital, it was determined that Mr. Liu has kidney damage, and the cause is related to his long-term use of analgesics.

2: The Reason for the Decreased Availability of Analgesics - Analgesics, such as "Qu Tong Pian," are inexpensive and effective painkillers. - They contain ingredients like aminopyrine, phenacetin, caffeine, and barbital. - These ingredients have safety concerns and have been phased out in many countries.

- In China, despite the regulation to eliminate aminopyrine and/or phenacetin-containing analgesics in 1982, they are still used in some regions.

 3: Consequences of Long-term Use of Analgesics - Prolonged use of analgesics can lead to kidney damage, bone marrow necrosis, uremia, and even cancer. - It can also cause drug dependence and tolerance, as well as neutropenia.

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